Invention Grant
US09101653B2 Influenza viruses with mutant PB2 gene segment as live attenuated vaccines
有权
具有突变体PB2基因片段的流感病毒作为活减毒疫苗
- Patent Title: Influenza viruses with mutant PB2 gene segment as live attenuated vaccines
- Patent Title (中): 具有突变体PB2基因片段的流感病毒作为活减毒疫苗
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Application No.: US13594611Application Date: 2012-08-24
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Publication No.: US09101653B2Publication Date: 2015-08-11
- Inventor: Yoshihiro Kawaoka , Gabriele Neumann , Makoto Ozawa
- Applicant: Yoshihiro Kawaoka , Gabriele Neumann , Makoto Ozawa
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Schwegman Lundberg & Woesnner, P.A.
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/145 ; C12N7/01 ; A61K35/76 ; C12N7/00 ; G01N33/569 ; A61K39/00
Abstract:
The invention provides a recombinant biologically contained influenza virus that is a PB2 knockout virus, e.g., one that is useful to generate a multivalent vaccine, and methods of making and using that virus.
Public/Granted literature
- US20130230552A1 INFLUENZA VIRUSES WITH MUTANT PB2 GENE SEGMENT AS LIVE ATTENUATED VACCINES Public/Granted day:2013-09-05
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