Invention Grant
- Patent Title: Targeting and in vivo imaging of tumor-associated macrophages
- Patent Title (中): 肿瘤相关巨噬细胞的靶向和体内成像
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Application No.: US13480350Application Date: 2012-05-24
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Publication No.: US09101674B2Publication Date: 2015-08-11
- Inventor: Kiavash Movahedi , Damya Laoui , Steve Schoonooghe , Geert Raes , Patrick De Baetselier , Jo Van Ginderachter , Nick Devoogdt , Tony Lahoutte
- Applicant: Kiavash Movahedi , Damya Laoui , Steve Schoonooghe , Geert Raes , Patrick De Baetselier , Jo Van Ginderachter , Nick Devoogdt , Tony Lahoutte
- Applicant Address: BE Gent BE Brussel
- Assignee: VIB VZW,Vrije Universiteit Brussel
- Current Assignee: VIB VZW,Vrije Universiteit Brussel
- Current Assignee Address: BE Gent BE Brussel
- Agency: TraskBritt, P.C.
- Main IPC: A61K51/10
- IPC: A61K51/10 ; A61K47/48 ; C07K16/28 ; B82Y5/00

Abstract:
The invention relates to activities and characteristics of tumor-associated macrophages (TAMs). In particular, immunoglobulin single variable domains are provided against markers of TAMs, and methods using the same for in vivo imaging of tumor cells, as well as cancer diagnostics and therapeutics.
Public/Granted literature
- US20120301394A1 TARGETING AND IN VIVO IMAGING OF TUMOR-ASSOCIATED MACROPHAGES Public/Granted day:2012-11-29
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