Invention Grant
- Patent Title: Azaindole derivatives as CFTR modulators
- Patent Title (中): Azaindole衍生物作为CFTR调节剂
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Application No.: US14031349Application Date: 2013-09-19
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Publication No.: US09102672B2Publication Date: 2015-08-11
- Inventor: Sara Hadida-Ruah , Jinglan Zhou , Mark Miller , Brian Bear
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Michael J. DiVerdi
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; A61K45/06
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20140024672A1 AZAINDOLE DERIVATIVES AS CFTR MODULATORS Public/Granted day:2014-01-23
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