Invention Grant
- Patent Title: Peptide aptamers that bind to the rep proteins of ssDNA viruses
- Patent Title (中): 结合ssDNA病毒rep蛋白的肽适体
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Application No.: US13437688Application Date: 2012-04-02
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Publication No.: US09102705B2Publication Date: 2015-08-11
- Inventor: Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- Applicant: Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- Applicant Address: US NC Raleigh
- Assignee: North Carolina State University
- Current Assignee: North Carolina State University
- Current Assignee Address: US NC Raleigh
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K7/06 ; A61K38/04 ; C07K14/00 ; C12Q1/00 ; A61K38/00
Abstract:
Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
Public/Granted literature
- US20120220519A1 Peptide Aptamers that Bind to the Rep Proteins of ssDNA Viruses Public/Granted day:2012-08-30
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