Invention Grant
- Patent Title: Polysialic acid derivatives
- Patent Title (中): 聚唾液酸衍生物
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Application No.: US13650048Application Date: 2012-10-11
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Publication No.: US09102714B2Publication Date: 2015-08-11
- Inventor: Dale Howard Hreczuk-Hirst , Sanjay Jain , Peter Laing , Gregory Gregoriadis , Ioannis Papaioannou
- Applicant: Lipoxen Technologies Limited
- Applicant Address: GB
- Assignee: Lipoxen Technologies Limited
- Current Assignee: Lipoxen Technologies Limited
- Current Assignee Address: GB
- Agency: One3 IP Management, P.C.
- Agent Dean G. Stathakis; Peter D. Weinstein
- Priority: EP03254988 20030812; EP03255200 20030821
- Main IPC: C07K1/107
- IPC: C07K1/107 ; C07K1/13 ; C08B37/00 ; C07K14/00 ; C07K1/00 ; A61K47/48
Abstract:
A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.
Public/Granted literature
- US20130144043A1 POLYSIALIC ACID DERIVATIVES Public/Granted day:2013-06-06
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