Invention Grant
- Patent Title: Compositions and methods of using chondroitinase ABCI mutants
- Patent Title (中): 使用软骨素酶ABCI突变体的组成和方法
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Application No.: US13849420Application Date: 2013-03-22
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Publication No.: US09102930B2Publication Date: 2015-08-11
- Inventor: Anthony O. Caggiano , Andrea Vecchione , Jennifer Iaci
- Applicant: ACORDA THERAPEUTICS, INC.
- Applicant Address: US PA Ardsley
- Assignee: Acorda Therapeutics, Inc.
- Current Assignee: Acorda Therapeutics, Inc.
- Current Assignee Address: US PA Ardsley
- Agency: Pepper Hamilton LLP
- Main IPC: C12N15/64
- IPC: C12N15/64 ; C12N15/00 ; C12N9/88 ; C07H21/04 ; C07K1/00 ; A61K38/00
Abstract:
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant enzymes exhibiting altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using such nucleic acid mutants encoding chondroitinase ABCI mutant enzymes is also provided.
Public/Granted literature
- US20130210082A1 COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS Public/Granted day:2013-08-15
Information query
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