Invention Grant
US09102969B2 Method for producing heterologous protein using yeast with disruption of VPS gene
有权
使用具有VPS基因破坏的酵母生产异源蛋白的方法
- Patent Title: Method for producing heterologous protein using yeast with disruption of VPS gene
- Patent Title (中): 使用具有VPS基因破坏的酵母生产异源蛋白的方法
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Application No.: US14004223Application Date: 2012-03-07
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Publication No.: US09102969B2Publication Date: 2015-08-11
- Inventor: Tozo Nishiyama , Yasuyoshi Sakai
- Applicant: Tozo Nishiyama , Yasuyoshi Sakai
- Applicant Address: JP Osaka-shi
- Assignee: KANEKA CORPORATION
- Current Assignee: KANEKA CORPORATION
- Current Assignee Address: JP Osaka-shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2011-054637 20110311
- International Application: PCT/JP2012/055825 WO 20120307
- International Announcement: WO2012/124567 WO 20120920
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N15/81 ; C12N15/67 ; C07K14/39 ; C12P21/02 ; C07K16/00
Abstract:
An object of the present invention it to improve the secretion productivity of a heterologous protein in a methanol-assimilating yeast. The present invention provides a method for producing a heterologous protein, characterized by comprising using a methanol-assimilating yeast with disruption of the VPS gene as a host for secretory production of the heterologous protein.
Public/Granted literature
- US20140106404A1 METHOD FOR PRODUCING HETEROLOGOUS PROTEIN USING YEAST WITH DISRUPTION OF VPS GENE Public/Granted day:2014-04-17
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