Invention Grant
- Patent Title: Process for the manufacture of a precursor of vitamin B1
- Patent Title (中): 制造维生素B1前体的方法
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Application No.: US11795957Application Date: 2006-01-24
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Publication No.: US09108925B2Publication Date: 2015-08-18
- Inventor: Werner Bonrath , Jocelyn Fischesser , Lisa Giraudi , Reinhard Karge
- Applicant: Werner Bonrath , Jocelyn Fischesser , Lisa Giraudi , Reinhard Karge
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: Nixon & Vanderhye P.C.
- Priority: EP05001859 20050128
- International Application: PCT/EP2006/000600 WO 20060124
- International Announcement: WO2006/079504 WO 20060803
- Main IPC: C07D239/42
- IPC: C07D239/42 ; C07D239/50 ; C07D417/06

Abstract:
The present invention relates to a novel process for the manufacture of Grewe-diamine comprising the following step: hydrolyzing a compound of formula (II), wherein R is hydrogen or straight- or branched chain C1-4 alkyl, with an aqueous alkali or alkaline-earth metal hydroxide solution, characterized in that the hydrolysis is carried out in the presence of an organic solvent.
Public/Granted literature
- US20080242863A1 Process For the Manufacture of a Precursor of Vitamin B1 Public/Granted day:2008-10-02
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