Invention Grant
- Patent Title: Synthesis process of dasatinib and intermediate thereof
- Patent Title (中): 达沙替尼及其中间体的合成方法
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Application No.: US13576637Application Date: 2011-01-30
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Publication No.: US09108954B2Publication Date: 2015-08-18
- Inventor: Rong Yan , Hao Yang , Wen Hou , Yongxiang Xu
- Applicant: Rong Yan , Hao Yang , Wen Hou , Yongxiang Xu
- Applicant Address: CN Jiangsu CN Jiangsu
- Assignee: Nan Jing Cavendish Bio-Engineering Technology Co., Ltd.,Rong Yan
- Current Assignee: Nan Jing Cavendish Bio-Engineering Technology Co., Ltd.,Rong Yan
- Current Assignee Address: CN Jiangsu CN Jiangsu
- Agency: Sunstone IP
- Priority: CN201010104295 20100202; CN201010169637 20100426
- International Application: PCT/CN2011/070828 WO 20110130
- International Announcement: WO2011/095126 WO 20110811
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14
Abstract:
Synthesis process of dasatinib is disclosed, which includes the step of reacting the compound of formula I with that of formula II to obtain the compound of formula III. Also disclosed is the compound of formula III which is used as an intermediate for synthesizing dasatinib. The substituents of R1, R2, R3 or R4 in formulae I, II or III are defined as in the description.
Public/Granted literature
- US20130030177A1 SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF Public/Granted day:2013-01-31
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