Invention Grant
- Patent Title: Pyro-glutamate Aβ targeting agents
- Patent Title (中): 焦氨酸A＆bgr 定位代理
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Application No.: US13949947Application Date: 2013-07-24
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Publication No.: US09109021B2Publication Date: 2015-08-18
- Inventor: Chris Dealwis
- Applicant: Case Western Reserve University
- Applicant Address: US OH Cleveland
- Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/18 ; A61K31/195 ; A61K39/00
Abstract:
A method of inhibiting amyloid beta aggregation in a mammal includes administering an amount of a pyro-Glu-(3-40/42)-Aβ targeting agent and/or fragment thereof that specifically binds to an epitope of the N terminus end of a pyro-Glu-(3-40/42)-Aβ effective to inhibit amyloid beta aggregation in the subject.
Public/Granted literature
- US20130302326A1 PYRO-GLUTAMATE ABETA TARGETING AGENTS Public/Granted day:2013-11-14
Information query
