Invention Grant
US09109232B2 Ets2 and Mesp1 generate cardiac progenitors from fibroblasts
有权
Ets2和Mesp1从成纤维细胞产生心脏祖细胞
- Patent Title: Ets2 and Mesp1 generate cardiac progenitors from fibroblasts
- Patent Title (中): Ets2和Mesp1从成纤维细胞产生心脏祖细胞
-
Application No.: US13915677Application Date: 2013-06-12
-
Publication No.: US09109232B2Publication Date: 2015-08-18
- Inventor: Robert J. Schwartz , Vladimir N. Potaman , Jose Francisco Islas
- Applicant: University of Houston , Texas Heart Institute , The Texas A&M University System
- Applicant Address: US TX Houston US TX Houston US TX College Station
- Assignee: University of Houston,Texas Heart Institute,The Texas A&M University System
- Current Assignee: University of Houston,Texas Heart Institute,The Texas A&M University System
- Current Assignee Address: US TX Houston US TX Houston US TX College Station
- Agency: Jackson Walker L.L.P.
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N5/077 ; C12N5/074
Abstract:
A method for modulating cell differentiation capabilities using heterologous gene expression. Some embodiments of the invention relate to a method for inducing a cardiac progenitor cell by delivering a reprogramming factor to the cell, wherein the reprogramming factor comprises ETS2 or a combination of ETS2 and Mesp1.
Public/Granted literature
- US20140004604A1 ETS2 AND MESP1 GENERATE CARDIAC PROGENITORS FROM FIBROBLASTS Public/Granted day:2014-01-02
Information query
IPC分类:
