Invention Grant
US09109240B2 Serinol production in glycerol catabolism deficient Escherichia coli strains
有权
甘油分解代谢缺乏大肠杆菌菌株中的丝氨醇生产
- Patent Title: Serinol production in glycerol catabolism deficient Escherichia coli strains
- Patent Title (中): 甘油分解代谢缺乏大肠杆菌菌株中的丝氨醇生产
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Application No.: US14018725Application Date: 2013-09-05
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Publication No.: US09109240B2Publication Date: 2015-08-18
- Inventor: Lukas Maksym , Alexander Steinbuechel , Bjoern Andreessen
- Applicant: BASF SE , Westfaelische Wilhelms-Universitaet Muenster
- Applicant Address: DE Ludwigshafen DE Muenster
- Assignee: BASF SE,Westfaelische Wilhelms Universitaet Muenster
- Current Assignee: BASF SE,Westfaelische Wilhelms Universitaet Muenster
- Current Assignee Address: DE Ludwigshafen DE Muenster
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C12P13/00
- IPC: C12P13/00 ; C12N9/10 ; C12N9/90
Abstract:
The invention is about E. coli host cells which are capable to convert glycerol to serinol. Furthermore, a process for producing serinol is disclosed, which comprises culturing E. coli host cells inactive for triosephosphate isomerase and active for dihydroxyacetone phosphate aminotransferase to convert glycerol to serinol, induction of conversion from glycerol to serinol by adding at least glycerol to the cell culture, and isolating serinol from the cell culture.
Public/Granted literature
- US20140080187A1 SERINOL PRODUCTION IN GLYCEROL CATABOLISM DEFICIENT ESCHERICHIA COLI STRAINS Public/Granted day:2014-03-20
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