Invention Grant
- Patent Title: Mass spectrometry assay for eIF4E and eIF4E regulon activity
- Patent Title (中): eIF4E和eIF4E调节活性的质谱分析
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Application No.: US13102669Application Date: 2011-05-06
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Publication No.: US09110074B2Publication Date: 2015-08-18
- Inventor: Gordon A. Jamieson Jr.
- Applicant: Gordon A. Jamieson Jr.
- Applicant Address: US MA Arlington
- Assignee: Translational Therapeutics, Inc.
- Current Assignee: Translational Therapeutics, Inc.
- Current Assignee Address: US MA Arlington
- Agency: Foley Hoag LLP
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; G01N33/68
Abstract:
Provided is a highly sensitive high throughput mass spectrometry-based quantitative assay for 4E/4E regulon pathway proteins has been developed which provides for single sample multiplexed analysis, as well as the analysis of protein phosphorylation states. It may be adapted for use as the first single sample analytical method of the 4E/4E regulon biological pathway.
Public/Granted literature
- US20110319295A1 MASS SPECTROMETRY ASSAY FOR eIF4E AND eIF4E REGULON ACTIVITY Public/Granted day:2011-12-29
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