According to one aspect of the present disclosure, a method and technique for data flow affinity for heterogeneous virtual machines is disclosed. The method includes: connecting first and second logical partitions to a shared virtual adapter, the first logical partition having a maximum receive unit (MRU) different than a MRU of the second logical partition; and responsive to receiving data by the shared virtual adapter destined for the first or second logical partitions, performing transmission control protocol (TCP) segmentation offload processing of the data by the shared virtual adapter utilizing the MRU of the first logical partition as the transmission unit for data destined for the first logical partition and utilizing the MRU of the second logical partition as the transmission unit for data destined for the second logical partition.