Invention Grant
US09119775B2 Use of pilocarpine for hypoptyalism treatment 有权
使用毛果芸香碱进行不适当治疗

Use of pilocarpine for hypoptyalism treatment
Abstract:
A method of treating hypoptyalism in a subject is provided. The method includes administering to the subject a pharmaceutical composition that includes pilocarpine and a bioadhesive polymer. The composition dissolves sublingually in the mouth of the subject and adheres to mucous tissues in the buccopharyngeal cavity. The pilocarpine then dissolves and binds to muscarine receptors present in cells of the subject's salivary glands, endobuccal submucous glands and submaxillary glands, is then absorbed by the cells thereby stimulating the glands to produce saliva.
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