Invention Grant
- Patent Title: Culturing circular ssDNA viruses for the production of vaccines
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Application No.: US12510844Application Date: 2009-07-28
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Publication No.: US09119806B2Publication Date: 2015-09-01
- Inventor: Hans Nauwynck , Gerald Misinzo , Sven Arnouts
- Applicant: Hans Nauwynck , Gerald Misinzo , Sven Arnouts
- Agency: Clark & Elbing LLP
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K39/12 ; A61K39/39 ; A61K38/21 ; A61K39/00
Abstract:
The present invention relates to the use of interferon in the in vitro cultivation of animal circular ssDNA virus such as Porcine Circovirus 2 or human TT virus in an animal cell line. Increased titres of animal circular ssDNA virus are obtained by addition of interferons or agents which ensure the production of endogenous interferons by said cell line and/or by the reduction of endosomal-lysosomal system acidification.
Public/Granted literature
- US20100166705A1 Culturing circular ssDNA viruses for the production of vaccines Public/Granted day:2010-07-01
Information query
