Invention Grant
- Patent Title: Combined measles-malaria vaccine
- Patent Title (中): 麻疹联合麻疹疫苗
-
Application No.: US13318701Application Date: 2010-05-03
-
Publication No.: US09119815B2Publication Date: 2015-09-01
- Inventor: Reinhard Glueck , Agata Fazio , Viviana Giannino , Martin A Billeter
- Applicant: Reinhard Glueck , Agata Fazio , Viviana Giannino , Martin A Billeter
- Applicant Address: IN Ahmedabad
- Assignee: CADILA HEALTHCARE LIMITED
- Current Assignee: CADILA HEALTHCARE LIMITED
- Current Assignee Address: IN Ahmedabad
- Agency: Ladas & Parry LLP
- Priority: IN1181/MUM/2009 20090505
- International Application: PCT/IN2010/000287 WO 20100503
- International Announcement: WO2010/128524 WO 20101111
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A61K39/165 ; A61K39/015 ; A61K38/20 ; C12N7/00 ; A61K35/13 ; A61K39/00

Abstract:
A combined measles-malaria vaccine containing different attenuated recombinant measles-malaria vectors comprising a heterologous nucleic acid encoding several Plasmodium falciparum antigens is described. Preferably, it relates to viral vectors that comprise nucleic acids encoding the circumsporozoite (CS) protein of P. falciparum, the merozoite surface protein 1 (MSP-1) of P. falciparum, and its derivatives (p-42; p-83-30-38) in its glycosylated and secreted forms, and apical membrane antigen1 (AMA1) of P. falciparum, in its anchored or secreted form. The viral vector stems from an attenuated measles virus, based on a strain that is used as a vaccine and is efficient in delivering the gene of interest and that binds to and infects the relevant immune cells efficiently.
Public/Granted literature
- US20120121538A1 COMBINED MEASLES-MALARIA VACCINE Public/Granted day:2012-05-17
Information query
IPC分类: