Invention Grant
US09119816B2 Method for prevention or treatment of diabetic angiogenesis impairment using C-peptide
有权
使用C肽预防或治疗糖尿病血管生成障碍的方法
- Patent Title: Method for prevention or treatment of diabetic angiogenesis impairment using C-peptide
- Patent Title (中): 使用C肽预防或治疗糖尿病血管生成障碍的方法
-
Application No.: US13987544Application Date: 2013-08-06
-
Publication No.: US09119816B2Publication Date: 2015-09-01
- Inventor: Kwon-Soo Ha , Young-Cheol Lim
- Applicant: KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION , AMOGREENTECH CO., LTD.
- Applicant Address: KR Gyeonggi-do
- Assignee: AMOGREENTECH CO., LTD.
- Current Assignee: AMOGREENTECH CO., LTD.
- Current Assignee Address: KR Gyeonggi-do
- Agency: Dickstien Shapiro LLP
- Main IPC: A61K38/16
- IPC: A61K38/16 ; C07K14/00 ; A61P3/10 ; A61K38/17
Abstract:
Disclosed are a method and composition for the prevention or treatment of diabetic angiogenesis impairment or diabetic wound-healing impairment, using C-peptide. Found to be able to induce angiogenesis through chemotactic migration of endothelial cells, cell migration to wounded areas, capillary-like network formation, and extracellular signal-regulated kinases 1/2 and Akt phosphorylation and nitric oxide production, C-peptide has prophylactic or therapeutic applications in a broad spectrum of various diabetic complications including diabetic angiogenesis impairment.
Public/Granted literature
- US20140128323A1 Method for prevention or treatment of diabetic angiogenesis impairment using C-peptide Public/Granted day:2014-05-08
Information query
IPC分类:
