Invention Grant
US09119831B2 Methods of manufacturing bioactive gels from extracellular matrix material
有权
从细胞外基质材料制造生物活性凝胶的方法
- Patent Title: Methods of manufacturing bioactive gels from extracellular matrix material
- Patent Title (中): 从细胞外基质材料制造生物活性凝胶的方法
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Application No.: US14332465Application Date: 2014-07-16
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Publication No.: US09119831B2Publication Date: 2015-09-01
- Inventor: Kimberly A. Kentner , Katherine A. Stuart , Abram D. Janis
- Applicant: ACell, Inc.
- Applicant Address: US MD Columbia
- Assignee: ACell, Inc.
- Current Assignee: ACell, Inc.
- Current Assignee Address: US MD Columbia
- Agency: Burns & Levinson LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; A61K35/37 ; A61K35/38 ; A61K35/407 ; A61K35/22 ; A61L27/36 ; A61L27/52 ; A61L27/54 ; A61K9/00 ; A61K35/12 ; A61K38/18
Abstract:
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
Public/Granted literature
- US20140342007A1 METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL Public/Granted day:2014-11-20
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