Invention Grant
US09119903B2 Porous composite with graded bioabsorbability, artificial bone using the same, and manufacturing method thereof
有权
具有分级生物吸收性的多孔复合材料,使用其的人造骨及其制造方法
- Patent Title: Porous composite with graded bioabsorbability, artificial bone using the same, and manufacturing method thereof
- Patent Title (中): 具有分级生物吸收性的多孔复合材料,使用其的人造骨及其制造方法
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Application No.: US14130841Application Date: 2012-07-04
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Publication No.: US09119903B2Publication Date: 2015-09-01
- Inventor: Junzo Tanaka , Toshiyuki Ikoma , Tomohiko Yoshioka , Takashi Yoshida
- Applicant: Junzo Tanaka , Toshiyuki Ikoma , Tomohiko Yoshioka , Takashi Yoshida
- Applicant Address: JP Tokyo
- Assignee: TOKYO INSTITUTE OF TECHNOLOGY
- Current Assignee: TOKYO INSTITUTE OF TECHNOLOGY
- Current Assignee Address: JP Tokyo
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: JP2011-148123 20110704
- International Application: PCT/JP2012/067113 WO 20120704
- International Announcement: WO2013/005778 WO 20130110
- Main IPC: A61F2/28
- IPC: A61F2/28 ; A61L27/58 ; A61L27/42 ; A61L27/46 ; A61L27/50 ; A61L27/56

Abstract:
The object of the present invention is to provide a calcium phosphate-collagen fiber composite which has an excellent mechanical property, can induce bone replacement by rapid bone remodeling, and can be used in a high-load region. The object can be solved by a porous composite comprising a calcium phosphate crystal and a collagen fiber at a weight ratio of 80:20 to 20:80, wherein (1) a bioabsorbability of the porous composite is graded, and (2) the density of the porous composite determined by gravimetric method is 300 to 1500 mg/cm3.
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