Invention Grant
- Patent Title: Process for the preparation of pleuromutilins
- Patent Title (中): 制剂的制备方法
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Application No.: US13699589Application Date: 2011-05-23
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Publication No.: US09120727B2Publication Date: 2015-09-01
- Inventor: Rosemarie Riedl , Werner Heilmayer , Lee Spence
- Applicant: Rosemarie Riedl , Werner Heilmayer , Lee Spence
- Applicant Address: AT Vienna
- Assignee: NABRIVA THERAPEUTICS AG
- Current Assignee: NABRIVA THERAPEUTICS AG
- Current Assignee Address: AT Vienna
- Agency: Workman Nydegger
- Priority: EP10450092 20100526
- International Application: PCT/AT2011/000237 WO 20110523
- International Announcement: WO2011/146954 WO 20111201
- Main IPC: C07C205/00
- IPC: C07C205/00 ; C07C229/00 ; C07C319/20 ; A61K31/215 ; C07C53/10 ; C07C57/145 ; C07C59/08 ; C07C319/14 ; C07C323/41 ; C07C323/43 ; C07C323/52 ; A01N37/00 ; A61K31/21

Abstract:
Process for the preparation of a compound of formula I in the form of a single stereoisomer in crystalline form, comprising deprotecting the amine group in a compound of formula IIa or in a mixture of a compound of formula IIa with a compound of formula IIb and isolating a compound of formula I from the reaction mixture; compounds and salts of compounds of formula I in crystalline form; pharmaceutical compositions comprising such salts; processes for the preparation of intermediates and intermediates in a process for the preparation of a compound of formula I.
Public/Granted literature
- US20130079400A1 PROCESS FOR THE PREPARATION OF PLEUROMUTILINS Public/Granted day:2013-03-28
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