Invention Grant
- Patent Title: Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
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Application No.: US12624126Application Date: 2009-11-23
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Publication No.: US09120744B2Publication Date: 2015-09-01
- Inventor: Daniel A. Lawrence , Cory Emal , Jacqueline Cale , Enming J. Su , Mark Warnock , Shih-Hon Li , Jeanne A. Cupp
- Applicant: Daniel A. Lawrence , Cory Emal , Jacqueline Cale , Enming J. Su , Mark Warnock , Shih-Hon Li , Jeanne A. Cupp
- Applicant Address: US MI Ann Arbor US MI Ypsilanti
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,EASTERN MICHIGAN UNIVERSITY
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,EASTERN MICHIGAN UNIVERSITY
- Current Assignee Address: US MI Ann Arbor US MI Ypsilanti
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07C311/29
- IPC: C07C311/29 ; C07C69/88 ; C07C69/90 ; C07C229/12 ; C07C229/34 ; C07C271/22 ; C07C271/54 ; C07H13/08
Abstract:
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
Public/Granted literature
- US20100137194A1 Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism Public/Granted day:2010-06-03
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