Invention Grant
- Patent Title: Uracil derivatives as AXL and c-MET kinase inhibitors
- Patent Title (中): 尿嘧啶衍生物作为AXL和c-MET激酶抑制剂
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Application No.: US14681981Application Date: 2015-04-08
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Publication No.: US09120778B2Publication Date: 2015-09-01
- Inventor: Reddeppa Reddy Dandu , Robert L. Hudkins , Kurt A. Josef , Catherine P. Prouty , Rabindranath Tripathy
- Applicant: Ignyta, Inc.
- Applicant Address: US CA San Diego
- Assignee: Ignyta, Inc.
- Current Assignee: Ignyta, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: C07D239/54
- IPC: C07D239/54 ; C07D403/12 ; A61K31/506 ; A61K31/4725 ; A61P35/00 ; C07D401/12

Abstract:
The present application provides compounds of Formula I or salt forms thereof, wherein Ra, Rb, Rc, Rd, D, W, R1a, R1b, R1c, Y, R3, X, E and G are as defined herein, compositions, methods of treatment and uses thereof.
Public/Granted literature
- US20150210670A1 URACIL DERIVATIVES AS AXL AND C-MET KINASE INHIBITORS Public/Granted day:2015-07-30
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