Invention Grant
- Patent Title: Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them
- Patent Title (中): 中氮茚化合物，其制备方法和含有它们的药物组合物
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Application No.: US14374071Application Date: 2013-01-23
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Publication No.: US09120791B2Publication Date: 2015-09-01
- Inventor: Thierry Le Diguarher , Patrick Casara , Jérôme-Benoît Starck , Jean-Michel Henlin , James Edward Paul Davidson , James Brooke Murray , Christopher John Graham , I-Jen Chen , Olivier Geneste , John Hickman , Stéphane Depil , Arnaud Le Tiran , Miklos Nyerges , Guillaume De Nanteuil
- Applicant: LES LABORATOIRES SERVIER , VERNALIS (R&D) Ltd.
- Applicant Address: FR Suresnes Cedex GB Winnersh
- Assignee: LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- Current Assignee: LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- Current Assignee Address: FR Suresnes Cedex GB Winnersh
- Agency: Hueschen and Sage
- Priority: FR1200193 20120124
- International Application: PCT/FR2013/050136 WO 20130123
- International Announcement: WO2013/110890 WO 20130801
- Main IPC: C07D471/00
- IPC: C07D471/00 ; A61K31/475 ; C07D471/04 ; C07D487/04 ; C07D491/052 ; C07D207/30 ; C07D211/06 ; C07D211/80 ; A61K31/496 ; A61K31/5377 ; A61K31/5383 ; A61K31/541 ; A61K31/55 ; A61K31/553 ; A61K45/06 ; A61N5/10 ; C07D498/04
Abstract:
Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
Public/Granted literature
- US20150051189A1 INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Public/Granted day:2015-02-19
Information query
