Invention Grant
- Patent Title: Peptide having a vascularization-suppressing activity and a use therefor
- Patent Title (中): 具有血管抑制活性的肽及其用途
-
Application No.: US13824789Application Date: 2011-09-08
-
Publication No.: US09121015B2Publication Date: 2015-09-01
- Inventor: Young Ae Joe , Hyun Kyung Kim
- Applicant: Young Ae Joe , Hyun Kyung Kim
- Applicant Address: KR Seoul
- Assignee: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
- Current Assignee: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: JHK Law
- Agent Joseph Hyosuk Kim
- Priority: KR10-2010-0091810 20100917
- International Application: PCT/KR2011/006651 WO 20110908
- International Announcement: WO2012/036412 WO 20120322
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/00 ; C12N9/72 ; C07K7/08 ; C07K14/515
Abstract:
Provided are peptides having anti-angiogenic activity and a use thereof, and more particularly, to peptides for inhibiting angiogenesis, the peptides including amino acid sequence with potent anti-angiogenic activity, a composition for inhibiting angiogenesis, the composition including the peptides, a medicine for inhibiting angiogenesis, the medicine including the composition, and a method for inhibiting angiogenesis using the peptides. The peptides for inhibiting angiogenesis, the peptides including the amino acid sequence of the invention provides not only potent inhibitory activity on proliferation, migration and tube formation of vascular endothelial cells, but also potent in vivo anti-angiogenic activity and inhibitory activity on proliferation and migration of cancer cells. Therefore, the peptide for inhibiting angiogenesis can be efficaciously used as a treatment for various diseases including cancer with abnormal regulation of angiogenesis.
Public/Granted literature
- US20130184215A1 PEPTIDE HAVING A VASCULARIZATION-SUPPRESSING ACTIVITY AND A USE THEREFOR Public/Granted day:2013-07-18
Information query
IPC分类:
