Invention Grant
- Patent Title: Method for producing glycolic acid using an inducible promoter
- Patent Title (中): 使用诱导型启动子生产乙醇酸的方法
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Application No.: US13704578Application Date: 2011-06-15
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Publication No.: US09121043B2Publication Date: 2015-09-01
- Inventor: Wanda Dischert , Rainer Figge , Philippe Soucaille
- Applicant: Wanda Dischert , Rainer Figge , Philippe Soucaille
- Applicant Address: FR Saint Beauzire
- Assignee: METABOLIC EXPLORER
- Current Assignee: METABOLIC EXPLORER
- Current Assignee Address: FR Saint Beauzire
- Agency: Miles & Stockbridge P.C.
- Priority: EP10305635 20100615
- International Application: PCT/EP2011/059884 WO 20110615
- International Announcement: WO2011/157728 WO 20111222
- Main IPC: C12P7/42
- IPC: C12P7/42 ; C12N15/70 ; C12N15/63

Abstract:
The present invention relates to use of inducible promoters in the production of glycolic acid by fermentation. The present invention concerns a method for the production of glycolic acid in a fermentative process comprising the following steps: culturing a modified microorganism in an appropriate culture medium comprising a source of carbon, modulating in said microorganism the expression of a target gene with an external stimulus, and recovering glycolic acid from the culture medium, wherein in said modified microorganism, the expression of at least one gene involved in glycolic acid production is under the control of a heterologous inducible promoter whose activity is modulated with said external stimulus. The invention also concerned the modified microorganism used in the method of glycolic acid production.
Public/Granted literature
- US20130089903A1 USE OF INDUCIBLE PROMOTERS IN THE PRODUCTION OF GLYCOLIC ACID Public/Granted day:2013-04-11
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