Predictive marker for EGFR inhibitor treatment

Invention Grant

US09121067B2 Predictive marker for EGFR inhibitor treatment 有权

Title translation: EGFR抑制剂治疗的预测标记

Patent Title: Predictive marker for EGFR inhibitor treatment
Patent Title (中): EGFR抑制剂治疗的预测标记
Application No.: US13854180

Application Date: 2013-04-01
Publication No.: US09121067B2

Publication Date: 2015-09-01
Inventor: Paul Delmar , Barbara Klughammer , Verena Lutz , Patricia McLoughlin
Applicant: Hoffmann-La Roche Inc.
Applicant Address: US NJ Nutley
Assignee: HOFFMANN-LA ROCHE INC.
Current Assignee: HOFFMANN-LA ROCHE INC.
Current Assignee Address: US NJ Nutley
Agent Jones Day
Priority: EP07114302 20070814
Main IPC: C12Q1/68
IPC: C12Q1/68 ; C07H21/04 ; A61K31/517

Abstract:

The present invention provides a biomarker which is predictive for the clinical benefit of EGFR inhibitor treatment in cancer patients.

Abstract(Chinese):

本发明提供了一种生物标志物，其可预测癌症患者中EGFR抑制剂治疗的临床益处。

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IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12Q	包含酶、核酸或微生物的测定或检验方法（免疫检测入G01N33/53）；其所用的组合物或试纸；这种组合物的制备方法；在微生物学方法或酶学方法中的条件反应控制
C12Q1/00	包含酶、核酸或微生物的测定或检验方法（带有条件测量或传感器的测定或试验装置，如菌落计数器入C12M1/34）；其组合物；这种组合物的制备方法
C12Q1/68	.包括核酸