A pressure pulsation dampening system for a pump that pressurizes a working fluid. In some embodiments, the dampening system includes a hydraulic cylinder, a valve, and a controller. The hydraulic cylinder has a piston that is movably disposed within a housing and divides the housing into a working fluid chamber and a hydraulic fluid chamber. An outlet of the pump is in fluid communication with the working fluid chamber, and the valve is in fluid communication with the hydraulic fluid chamber. The controller is operable to actuate the valve to a first configuration, wherein pressurized hydraulic fluid is supplied to the hydraulic fluid chamber, and to a second configuration, wherein hydraulic fluid is exhausted from the hydraulic fluid chamber. The piston is movable under fluid pressure, whereby working fluid is relieved from the outlet to the working fluid chamber or supplied to the outlet from the working fluid chamber.