Invention Grant
US09121859B2 Compounds and methods for determination of FKBP-binding immunosuppressant drugs
有权
用于测定FKBP结合免疫抑制药物的化合物和方法
- Patent Title: Compounds and methods for determination of FKBP-binding immunosuppressant drugs
- Patent Title (中): 用于测定FKBP结合免疫抑制药物的化合物和方法
-
Application No.: US13693229Application Date: 2012-12-04
-
Publication No.: US09121859B2Publication Date: 2015-09-01
- Inventor: Yi Feng Zheng , Tie Q. Wei
- Applicant: Siemens Healthcare Diagnostics Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee Address: US NY Tarrytown
- Agent Theodore J. Leitereg
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K31/436 ; G01N33/94
Abstract:
Compositions are disclosed for releasing an FKBP-binding immunosuppressant drug from endogenous binding substances in a sample suspected of containing the FKBP-binding immunosuppressant drug. The compositions include sirolimus derivatives that are modified with a bulky organic radical in the triene portion of the sirolimus molecule. The compositions may be employed in conjunction with assays for an FKBP-binding immunosuppressant drug in a sample suspected of containing the drug.
Public/Granted literature
- US20140154706A1 Compounds and Methods for Determination of FKBP-Binding Immunosuppressant Drugs Public/Granted day:2014-06-05
Information query
IPC分类:
