A frame with a sensing function includes a frame structure, a sensor and a processing unit. The processing unit is electrically connected to the sensor. The frame structure is configured for hanging on a display unit. The sensor senses a touched position set of the display unit for position setting. The processing unit includes a parameter calculating module and a parameter providing module. The parameter calculating module calculates a position transformation parameter between the hanged frame structure and the display unit according to the touched position set. The parameter providing module provides the position transformation parameter, such that a display content displayed on the display unit is controlled according to at least one touched position for operation sensed by the sensor and the position transformation parameter.