A patient monitoring system may be configured to acquire data signals relating to various physiological parameters of a patient. For example, the patient monitoring system may be used to determine or record a patient's blood pressure, heart rate, temperature, and/or other physiological parameters. The patient monitoring system may process the data signals and generate patient parameter information. The patient parameter information may be displayed on a display unit. The patient monitoring system may be configured to dynamically reconfigure a visual display of the patient parameter information based on the orientation (e.g., portrait or landscape) of the patient monitoring system. Additionally, the patient monitoring system may be configured to selectively enter a transport mode, in which the touch screen and/or user inputs are locked or partially locked. The patient monitoring system may automatically enter a transport mode when the display unit is rotated to a landscape orientation.