An apparatus comprises a surgical instrument having a proximal end and a distal end. The proximal end may comprise a handle. The distal end may comprise a cutter and a stapler. The apparatus may further comprise a staple for use with the stapler. The staple may comprise an inner channel extending along at least a portion of the length of the staple. The apparatus may further comprise an agent contained in the inner channel, which may be used to coagulate a surgical site where surgical instrument is used. The agent may facilitate coagulation of the fluids at a surgical site once the staples are anchored to the surgical site.