Invention Grant
US09125805B2 Stable formulations for parenteral injection of small molecule drugs
有权
用于肠胃外注射小分子药物的稳定制剂
- Patent Title: Stable formulations for parenteral injection of small molecule drugs
- Patent Title (中): 用于肠胃外注射小分子药物的稳定制剂
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Application No.: US13829937Application Date: 2013-03-14
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Publication No.: US09125805B2Publication Date: 2015-09-08
- Inventor: Steven J. Prestrelski , Nancy Scott
- Applicant: Xeris Pharmaceuticals, Inc.
- Applicant Address: US TX Austin
- Assignee: Xeris Pharmaceuticals, Inc.
- Current Assignee: Xeris Pharmaceuticals, Inc.
- Current Assignee Address: US TX Austin
- Agency: Norton Rose Fulbright US LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K31/5513 ; A61K47/14 ; A61K47/10 ; A61K47/22 ; A61K47/20 ; A61K9/08 ; A61K31/137 ; A61K31/167 ; A61K31/352 ; A61K31/4045 ; A61K31/4196 ; A61K31/496 ; A61K31/55 ; A61K31/675 ; A61K31/7036
Abstract:
Disclosed is a stable liquid formulation for parenteral injection comprising a biocompatible non-aqueous solvent and a small molecule drug, or a salt thereof, solubilized within the non-aqueous solvent, wherein the liquid formulation comprises less than 10% by weight residual water, and wherein the volume of the liquid formulation to be parenterally injected is from 0.1 μl to 3 ml.
Public/Granted literature
- US20140005135A1 STABLE FORMULATIONS FOR PARENTERAL INJECTION OF SMALL MOLECULE DRUGS Public/Granted day:2014-01-02
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