Invention Grant
- Patent Title: OMV vaccines
- Patent Title (中): OMV疫苗
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Application No.: US13702949Application Date: 2011-06-10
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Publication No.: US09125864B2Publication Date: 2015-09-08
- Inventor: Renata Maria Grifantini , Erika Bartolini , Oretta Finco , Guido Grandi
- Applicant: Renata Maria Grifantini , Erika Bartolini , Oretta Finco , Guido Grandi
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Robins Law Group
- Agent Roberta L. Robins
- Priority: GB1009861.4 20100611
- International Application: PCT/IB2011/002341 WO 20110610
- International Announcement: WO2011/161551 WO 20111229
- Main IPC: A61K39/118
- IPC: A61K39/118 ; A61K45/00 ; A61K39/02 ; A61K39/385 ; C12N1/20 ; C12N1/00 ; C12N1/12 ; C07K14/245 ; C07K14/295 ; C12P21/02 ; A61K39/00
Abstract:
The invention is in the field of outer membrane vesicles (OMV) and their uses. More particularly the present invention provides OMV obtained from a bacterium being an ompA mutant and/or a mutant in one or more components of the TolPal complex and presenting a heterologous antigen on its surface. The heterologous antigen is selected from the group consisting of Chlamydia trachomatis CT823, CT681, CT372, CT443, CT043, CT733, CT279, CT601 and CT153 for the treatment, prevention or diagnosis of Chlamydia infection.
Public/Granted literature
- US20130195907A1 OMV VACCINES Public/Granted day:2013-08-01
Information query
