Invention Grant
- Patent Title: Method for expanding monocytes
- Patent Title (中): 扩增单核细胞的方法
-
Application No.: US14072494Application Date: 2013-11-05
-
Publication No.: US09125869B2Publication Date: 2015-09-08
- Inventor: Michael Sieweke
- Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
- Applicant Address: FR Paris FR Paris
- Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris FR Paris
- Agency: McAndrews, Held & Malloy Ltd.
- Priority: EP07300717 20070111
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00 ; A61K35/15 ; C07K14/82 ; C12N5/0784 ; C12N5/0786 ; G01N33/50 ; A61K38/00 ; A61K35/12 ; A61K39/00
Abstract:
The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signalling.
Public/Granted literature
- US20140127268A1 Method for Expanding Monocytes Public/Granted day:2014-05-08
Information query
