Invention Grant
US09125881B2 Monoglyceride of acetoacetate and derivatives for the treatment of neurological disorders
有权
乙酰乙酸的单酸甘油酯和治疗神经系统疾病的衍生物
- Patent Title: Monoglyceride of acetoacetate and derivatives for the treatment of neurological disorders
- Patent Title (中): 乙酰乙酸的单酸甘油酯和治疗神经系统疾病的衍生物
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Application No.: US13054053Application Date: 2009-07-02
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Publication No.: US09125881B2Publication Date: 2015-09-08
- Inventor: Samuel T. Henderson
- Applicant: Samuel T. Henderson
- Applicant Address: US CO Broomfield
- Assignee: Accera, Inc.
- Current Assignee: Accera, Inc.
- Current Assignee Address: US CO Broomfield
- Agency: Swanson & Bratschun, L.L.C.
- International Application: PCT/US2009/049609 WO 20090702
- International Announcement: WO2010/003114 WO 20100107
- Main IPC: A61K31/22
- IPC: A61K31/22 ; A61K31/7004 ; A61P25/28 ; A23L1/30 ; A23L2/52 ; A61K9/00 ; A61K9/10 ; A61K9/20 ; A61K9/48 ; A61K31/047
Abstract:
This invention relates to methods of using the monoglyceride of acetoacetate and metabolic precursors for the treatment, prevention, inhibition or alleviation of neurological diseases associated with neuronal hypometabolism, such as Alzheimer's disease, Parkinson's disease, Friedreich's Ataxia (FRDA), GLUT1-deficient Epilepsy, Leprechaunism and Rabson-Mendenhall Syndrome, Coronary Arterial Bypass Graft (CABG) dementia, anesthesia induced memory loss, age associated memory impairment (AAMI), Traumatic Brain Injury (TBI), Huntington's disease and many others.
Public/Granted literature
- US20110178032A1 Monoglyceride of Acetoacetate and Derivatives for the Treatment of Neurological Disorders Public/Granted day:2011-07-21
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