Invention Grant
- Patent Title: EGFR aptamer inhibitor for use in therapy and diagnosis
- Patent Title (中): EGFR适体抑制剂用于治疗和诊断
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Application No.: US13876111Application Date: 2011-10-10
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Publication No.: US09125930B2Publication Date: 2015-09-08
- Inventor: Vittorio De Franciscis , Laura Cerchia
- Applicant: Vittorio De Franciscis , Laura Cerchia
- Applicant Address: IT Rome
- Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
- Current Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE
- Current Assignee Address: IT Rome
- Agency: Lucas & Mercanti, LLP
- Priority: ITRM2010A0536 20101012
- International Application: PCT/EP2011/067629 WO 20111010
- International Announcement: WO2012/049112 WO 20120419
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/11 ; A61K31/7088 ; C12N15/115 ; A61K39/395 ; A61K45/00
Abstract:
The present invention concerns a nucleotide aptamer having the sequence 5′ GCCUUAGUAACGUGCUUUGAUGUCGAUUCGACAGGAGGC3′ (SEQ ID No. 1) for use in the treatment and/or prevention and/or diagnosis of an EGFR induced disorder and a pharmaceutical composition comprising the same. The invention also relates to a method for the diagnosis of a EGFR induced disorder in a patient from which a sample is obtained and relative diagnostic kit.
Public/Granted literature
- US20130177556A1 EGFR APTAMER INHIBITOR FOR USE IN THERAPY AND DIAGNOSIS Public/Granted day:2013-07-11
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