Invention Grant
US09125949B2 Direct utilization of plasma proteins for the in vivo assembly of protein-drug/imaging agent conjugates, nanocarriers and coatings for biomaterials 有权
直接利用血浆蛋白质用于生物材料的蛋白质 - 药物/成像剂缀合物,纳米载体和涂层的体内装配

  • Patent Title: Direct utilization of plasma proteins for the in vivo assembly of protein-drug/imaging agent conjugates, nanocarriers and coatings for biomaterials
  • Patent Title (中): 直接利用血浆蛋白质用于生物材料的蛋白质 - 药物/成像剂缀合物,纳米载体和涂层的体内装配
  • Application No.: US12649941
    Application Date: 2009-12-30
  • Publication No.: US09125949B2
    Publication Date: 2015-09-08
  • Inventor: Robby A. Petros
  • Applicant: Robby A. Petros
  • Applicant Address: US TX Denton
  • Assignee: University of North Texas
  • Current Assignee: University of North Texas
  • Current Assignee Address: US TX Denton
  • Agency: Chalker Flores, LLP
  • Agent Chainey P. Singleton; Edwin S. Flores
  • Main IPC: A61K39/00
  • IPC: A61K39/00 A61K47/48
Direct utilization of plasma proteins for the in vivo assembly of protein-drug/imaging agent conjugates, nanocarriers and coatings for biomaterials
Abstract:
The present invention includes compositions and methods for making and using a drug conjugated to a peptide or protein that binds specifically to a ligand in vivo, wherein the conjugate binds to its ligand in vivo and increases the half-life of the drug.
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