The present invention relates to a machine tool, in particular a lathe, comprising a machine frame 1 having a first carrier side TS1 and a second carrier side TS2, wherein the machine frame 1 includes a first carrier portion 1a, a second carrier portion 1b and a middle carrier portion 1c which is arranged between the first and second carrier portions, a first spindle carrier 31 which is arranged on the first carrier side TS1 of the first carrier portion 1a and which holds a first work spindle 21, a first spindle carrier slide 42 which is arranged on the first or second carrier side of the second carrier portion 1b and on which a second spindle carrier 32 is arranged which holds a second work spindle 22 facing the first work spindle 21, wherein the spindle axes are aligned in parallel, in particular coaxially, and wherein the second spindle carrier 32 can be moved in direction W parallel to the spindle axes, and a second tool carrier slide 52 which is arranged on the first carrier side TS1 of the middle portion 1c and on which a tool carrier 62 for tools is arranged, wherein the second tool carrier slide 52 is arranged on the first carrier side TS1 between the first spindle carrier 31 and the second spindle carrier 32.