Efficient methods for the production of long-chain unsaturated dicarboxylic compounds are disclosed. Unsaturated dicarboxylic compounds may be prepared from a reaction mixture containing unsaturated carboxylic compounds in the presence of one or more catalysts. In addition to the unsaturated dicarboxylic compounds, alkene compounds may also be produced. The alkene compounds may be removed from the reaction mixture under reduced pressure. The method may also use a wiped-film still as a means to remove the alkene compounds from the reaction mixture. Reaction conditions may be monitored and/or controlled through the use of one or more electronic system(s) in communication with a variety of sensors and controllable devices.