Invention Grant
- Patent Title: Amido compounds and their use as pharmaceuticals
- Patent Title (中): 酰胺化合物及其作为药物的用途
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Application No.: US13243565Application Date: 2011-09-23
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Publication No.: US09126927B2Publication Date: 2015-09-08
- Inventor: Wenqing Yao , Jincong Zhuo , Meizhong Xu , Brian W. Metcalf , Chunhong He , Ding-Quan Qian , Colin Zhang
- Applicant: Wenqing Yao , Jincong Zhuo , Meizhong Xu , Brian W. Metcalf , Chunhong He , Ding-Quan Qian , Colin Zhang
- Applicant Address: US DE Wilmington US DE Wilmington
- Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee Address: US DE Wilmington US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D209/96
- IPC: C07D209/96 ; C07D307/94 ; C07D207/06 ; C07D207/08 ; C07D207/10 ; C07D207/12 ; C07D207/14 ; C07D207/16 ; C07D207/27 ; C07D209/08 ; C07D209/42 ; C07D209/44 ; C07D209/52 ; C07D209/62 ; C07D209/70 ; C07D211/16 ; C07D211/18 ; C07D211/22 ; C07D211/34 ; C07D211/46 ; C07D211/48 ; C07D211/52 ; C07D211/58 ; C07D211/64 ; C07D211/66 ; C07D211/70 ; C07D213/38 ; C07D217/06 ; C07D217/26 ; C07D221/20 ; C07D295/185 ; C07D333/34 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D401/14 ; C07D403/04 ; C07D405/04 ; C07D405/14 ; C07D413/10 ; C07D413/14 ; C07D417/04 ; C07D471/04 ; C07D471/10 ; C07D487/04 ; C07D487/08 ; C07D487/10 ; C07D491/10 ; C07D491/20 ; C07D493/10 ; C07D495/04 ; C07D498/20 ; C07D513/10
Abstract:
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Public/Granted literature
- US20120015928A1 Amido Compounds And Their Use As Pharmaceuticals Public/Granted day:2012-01-19
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