Invention Grant
- Patent Title: Phosphatidylcholine transfer protein inhibitors
- Patent Title (中): 磷脂酰胆碱转移蛋白抑制剂
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Application No.: US13390910Application Date: 2010-08-17
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Publication No.: US09126938B2Publication Date: 2015-09-08
- Inventor: David Cohen , Neil Wagle , Gregory D. Cuny , Jun Xian , Marcie Glicksman , Ross L. Stein , Ekaterina Y. Shishova
- Applicant: David Cohen , Neil Wagle , Gregory D. Cuny , Jun Xian , Marcie Glicksman , Ross L. Stein , Ekaterina Y. Shishova
- Applicant Address: US MA Boston
- Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2010/045752 WO 20100817
- International Announcement: WO2011/022393 WO 20110224
- Main IPC: C07D239/42
- IPC: C07D239/42 ; A61K31/505 ; A61P1/16 ; A61P3/04 ; A61P3/10 ; A61P9/10 ; A61P11/06 ; C07D213/60 ; A61K31/44 ; C07D239/32
Abstract:
This invention relates to compounds of Formulas I, II, and III, and their use as inhibitors of phosphatidylcholine transfer protein (PC-TP). The invention further relates to pharmaceutical compositions and methods of treatment of disorders related to the inhibition of PC-TP using the compounds of Formulas I, II, and III. Such disorders include obesity and disorders associated with obesity.
Public/Granted literature
- US20120264756A1 Phosphatidylcholine Transfer Protein Inhibitors Public/Granted day:2012-10-18
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