Invention Grant
US09126981B2 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions
有权
用于治疗癌症和其他CBP /连环素介导的疾病和病症的α螺旋模拟组合物
- Patent Title: Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions
- Patent Title (中): 用于治疗癌症和其他CBP /连环素介导的疾病和病症的α螺旋模拟组合物
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Application No.: US14247105Application Date: 2014-04-07
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Publication No.: US09126981B2Publication Date: 2015-09-08
- Inventor: Hiroyuki Kouji , Yuji Kogami , Takenao Odagami
- Applicant: PRISM BioLab Corporation
- Applicant Address: JP Yokohama-shi
- Assignee: PRISM BioLab Co., Ltd.
- Current Assignee: PRISM BioLab Co., Ltd.
- Current Assignee Address: JP Yokohama-shi
- Agency: Davis Wright Tremaine LLP
- Agent Barry L. Davison
- Main IPC: C07D215/38
- IPC: C07D215/38 ; C07D409/12 ; C07D487/14 ; C07D487/22 ; C07D498/04 ; C07C271/66 ; C07C275/18 ; C07C311/48 ; C07D213/40 ; C07D215/14 ; C07D277/82 ; C07D309/12 ; C07D333/58 ; C07D401/12
Abstract:
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating thereto, and methods relating thereto, are disclosed. Applications of these compounds in the treatment of medical conditions, e.g., cancer diseases, fibrotic diseases, and pharmaceutical compositions comprising the mimetics are further disclosed.
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