Invention Grant
- Patent Title: Glucosylceramide synthase inhibitors
- Patent Title (中): 葡萄糖神经酰胺合酶抑制剂
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Application No.: US14471958Application Date: 2014-08-28
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Publication No.: US09126993B2Publication Date: 2015-09-08
- Inventor: Elyse Bourque , Bradford Hirth , Renato Sklerj , Elina Makino , Fazeela Morshed , Lingyun Li , Paul Mason , John P. Leonard , James Lillie , Hanlan Liu , Mary A. Cromwell , Bing Wang , Thomas O'Shea
- Applicant: GENZYME CORPORATION
- Applicant Address: US MA Cambridge
- Assignee: Genzyme Corporation
- Current Assignee: Genzyme Corporation
- Current Assignee Address: US MA Cambridge
- Agent Jennifer D. Tousignant
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/44 ; C07D453/02 ; A61K38/47 ; A61K31/439 ; A61K31/454 ; C07D453/00
Abstract:
The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
Public/Granted literature
- US20140371460A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Public/Granted day:2014-12-18
Information query
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