Invention Grant
US09127001B2 Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
有权
取代的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶，它们作为药物的用途，以及包含它们的药物制剂
![Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them](/docs/US/2015-09-08/US09127001B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
- Patent Title (中): 取代的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶，它们作为药物的用途，以及包含它们的药物制剂
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Application No.: US14342744Application Date: 2011-09-16
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Publication No.: US09127001B2Publication Date: 2015-09-08
- Inventor: Laurent Bialy , Katrin Lorenz , Klaus Wirth , Klaus Steinmeyer , Gerhard Hessler , Josef Pernerstorfer , Joachim Brendel
- Applicant: Laurent Bialy , Katrin Lorenz , Klaus Wirth , Klaus Steinmeyer , Gerhard Hessler , Josef Pernerstorfer , Joachim Brendel
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: McDonnell Boehnen Hulbert & Berghoff
- International Application: PCT/EP2011/066061 WO 20110916
- International Announcement: WO2013/037415 WO 20130321
- Main IPC: C07D513/02
- IPC: C07D513/02 ; C07D471/04 ; C07D471/18
![Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them](/abs-image/US/2015/09/08/US09127001B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula (I) act on the TASK-1 potassium channel. The compounds are particularly suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.
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