Invention Grant
- Patent Title: LLT-1 antibodies with new functional properties
- Patent Title (中): 具有新功能特性的LLT-1抗体
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Application No.: US13807505Application Date: 2011-06-28
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Publication No.: US09127052B2Publication Date: 2015-09-08
- Inventor: Petrus Johannes Louis Spee , Peter Andreas Nicolai Reumert Wagtmann , Stefan Zahn , Elisabeth D. Galsgaard , Birgitte Friedrichsen , Véronique Braud
- Applicant: Petrus Johannes Louis Spee , Peter Andreas Nicolai Reumert Wagtmann , Stefan Zahn , Elisabeth D. Galsgaard , Birgitte Friedrichsen , Véronique Braud
- Applicant Address: FR Paris
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Paris
- Agency: Banner & Witcoff, Ltd.
- Priority: EP10167668 20100629; EP10168095 20100701; EP10169409 20100713
- International Application: PCT/EP2011/060819 WO 20110628
- International Announcement: WO2012/000994 WO 20120105
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/18
Abstract:
The present invention relates to monoclonal antibodies that are capable of specifically binding to lectin-like transcript 1 (LLT1), to polynucleotides encoding such antibodies and to cells that express such antibodies. Antibodies of the invention have utility in the treatment of autoimmune diseases and cancer, in which LLT1-and CD161-expressing cells play a role in disease pathogenesis.
Public/Granted literature
- US20130164299A1 LLT-1 ANTIBODIES WITH NEW FUNCTIONAL PROPERTIES Public/Granted day:2013-06-27
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