Invention Grant
- Patent Title: Anti-human HER3 antibodies and uses thereof
- Patent Title (中): 抗人HER3抗体及其用途
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Application No.: US14118747Application Date: 2012-05-21
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Publication No.: US09127065B2Publication Date: 2015-09-08
- Inventor: Thierry Chardes , Andre Pelegrin , Christel Larbouret , Nadege Gaborit , Yassamine Lazrek
- Applicant: Thierry Chardes , Andre Pelegrin , Christel Larbouret , Nadege Gaborit , Yassamine Lazrek
- Applicant Address: FR Paris FR Montpellier Cedex FR Montpellier Cedex
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre Val d'Aurelle—Paul Lamarque,Universite de Montpellier 1
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre Val d'Aurelle—Paul Lamarque,Universite de Montpellier 1
- Current Assignee Address: FR Paris FR Montpellier Cedex FR Montpellier Cedex
- Agency: Whitham Curtis Chistofferson & Cook, PC
- Priority: EP11305607 20110519
- International Application: PCT/EP2012/059402 WO 20120521
- International Announcement: WO2012/156532 WO 20121122
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/32
Abstract:
The present invention provides for isolated anti-human-HER3 antibodies or fragments thereof. More particularly the present invention provides an isolated monoclonal antibody that specifically binds to the extracellular domain of HER-3 and competes for binding to the extracellular domain of human HER-3 with the antibody produced obtainable from hybridoma deposited as CNCM-I-4486. The antibodies described in the present invention are useful for the treatment of cancer.
Public/Granted literature
- US20140112931A1 ANTI-HUMAN HER3 ANTIBODIES AND USES THEREOF Public/Granted day:2014-04-24
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