Invention Grant
US09127086B2 CD31 peptides in the treatment of thrombotic and autoimmune disorders
有权
CD31肽治疗血栓形成和自身免疫性疾病
- Patent Title: CD31 peptides in the treatment of thrombotic and autoimmune disorders
- Patent Title (中): CD31肽治疗血栓形成和自身免疫性疾病
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Application No.: US13001513Application Date: 2009-06-30
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Publication No.: US09127086B2Publication Date: 2015-09-08
- Inventor: Giuseppina Caligiuri , Antonino Nicoletti
- Applicant: Giuseppina Caligiuri , Antonino Nicoletti
- Applicant Address: FR Paris
- Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale)
- Current Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale)
- Current Assignee Address: FR Paris
- Agency: Whitham, Curtis, Christofferson & Cook, P.C.
- Priority: EP08305360 20080630
- International Application: PCT/EP2009/058188 WO 20090630
- International Announcement: WO2010/000741 WO 20100107
- Main IPC: A61K38/03
- IPC: A61K38/03 ; A61K38/04 ; C07K4/00 ; C07K7/00 ; C07K14/705 ; A61K38/00
Abstract:
The present invention stems from the finding that the extracellular domain of CD31 proteins present on blood leukocytes is shed and released in the circulation as a soluble form of CD31. The invention relates to peptides corresponding to fragments of CD31 that inhibit T-cell response, and to their use in the treatment of thrombotic disorders such as atherothrombosis and autoimmune disorders.
Public/Granted literature
- US20120010136A1 USE OF CD31 PEPTIDES IN THE TREATMENT OF THROMBOTIC AND AUTOIMMUNE DISORDERS Public/Granted day:2012-01-12
Information query
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