Invention Grant
- Patent Title: Enzymes resistant to photodamage
- Patent Title (中): 耐光损害的酶
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Application No.: US12384110Application Date: 2009-03-30
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Publication No.: US09127259B2Publication Date: 2015-09-08
- Inventor: Keith Bjornson , Sonya Clark , Insil Park , Fred Christians
- Applicant: Keith Bjornson , Sonya Clark , Insil Park , Fred Christians
- Applicant Address: US CA Menlo Park
- Assignee: Pacific Biosciences of California, Inc.
- Current Assignee: Pacific Biosciences of California, Inc.
- Current Assignee Address: US CA Menlo Park
- Agent Monicia Elrod-Erickson
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12P19/34 ; C12Q1/68
Abstract:
Provided are compositions comprising modified DNA polymerases that exhibit improved photostability compared to the parental polymerases from which they were derived. Provided are methods for generating enzymes, such as DNA polymerases, with the aforementioned phenotype. Provided are methods of using polymerases with increased resistance to photodamage to make a DNA or to sequence a DNA template.
Public/Granted literature
- US20100093555A1 Enzymes resistant to photodamage Public/Granted day:2010-04-15
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