Invention Grant
- Patent Title: Serpinc1 iRNA compositions and methods of use thereof
- Patent Title (中): Serpinc1 iRNA组合物及其使用方法
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Application No.: US13837129Application Date: 2013-03-15
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Publication No.: US09127274B2Publication Date: 2015-09-08
- Inventor: Akin Akinc , Alfica Sehgal , Ivanka Toudjarska , Donald Foster , Stuart Milstein , Brian Bettencourt , Martin A. Maier , Klaus Charisse , Satyanarayana Kuchimanchi , Kallanthottathil G. Rajeev , Muthiah Monaharan
- Applicant: Alnylam Pharmaceuticals
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the Serpinc1 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of Serpinc1 and methods of treating subjects having a bleeding disorder, such as a hemophilia.
Public/Granted literature
- US20130317081A1 SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2013-11-28
Information query
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